| Courses | Semester Hrs | Quarter Hrs |
| General Biology I & II with labs (Coursework in botany, ecology, entomology, anatomy, or physiology will not fulfill the biology requirement.) | 8 | 12 |
| General Chemistry I & II with labs* | 8 | 12 |
| General Physics I & II with labs* | 8 | 12 |
| Human or Mammalian Physiology (If enrolled in a combined anatomy/physiology course, 6 semester hours will be required.) | 3 | 4.5 |
| English (including Composition) | 6 | 9 |
| Statistics | 3 | 4.5 |
| Electives (Creighton undergraduate students must complete 6 hours of Theology among the elective hours.) | 54 | 82 |
| Total | 90 | 136 |
*The chemistry and physics courses must be a two-semester, eight-hour or equivalent course sequence. A course sequence is considered to be a correlated pair of courses offering in-depth coverage of a specific field and must be at a level such that the courses would be acceptable as prerequisites to advance toward a baccalaureate degree in that discipline. Survey courses, non-sequential courses, courses without associated laboratories, courses designed for non-science majors, online science courses utilizing a laboratory kit, or abbreviated courses targeted toward health science majors are not acceptable as prerequisite science courses. Applicants must have completed 16 of the 27 prerequisite science courses or equivalent prior to the application deadline.
An unofficial transcript evaluation for prerequisite fulfillment may be requested.
At the Creighton University Medical Center 2006 Commencement, Fr. John P. Schlegel, S.J., Creighton University President stated, "Your professors have challenged you to be leaders in your professions. As a student, you were expected to go beyond the ordinary to achieve the extraordinary. Your patients will expect no less of you. Do not disappoint them. Ethics, service, and excellence: These three words have been consistent across the 127 years of Creighton's existence; they serve as the foundation for what we do today. You will carry these with you; they are marks of a Creighton health care professional."
Julie Ekstrum, DPT, an assistant professor of physical therapy at Creighton University, is now a Certified Clinical Specialist in Cardiopulmonary Physical Therapy. Ekstrum will be formally recognized by the American Physical Therapy Association (APTA) at the Combined Sections Meeting in February 2008.